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Opana ER 5mg




To relieve severe ongoing pain, Opana ER 5mg extended-release is prescribed. The drug belongs to a class of drugs known as long-acting opioid analgesics. You feel and respond to pain differently when you use it because it works in your brain. Do not use the extended-release form of Opana ER 5mg to relieve mild pain or pain that goes away This medication is not for occasional (“as needed”) use.

How to use Opana ER 10 Mg Tablet, Extended Release

Read the Medication Guide provided by your pharmacist before you start taking Opana ER 5mg extended-release each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication on a regular schedule as directed by your doctor, not as needed for sudden (breakthrough) pain.

As directed by your doctor, take this medication by mouth every 12 hours without food (at least 1 hour before or 2 hours after eating). You should swallow the tablets whole. Avoid breaking, chewing, dissolving, or crushing them. Before taking the tablets, do not soak, lick, or wet them. Ask your doctor or pharmacist how to decrease nausea (such as lying down for 1 to 2 hours without moving your head much).


Overdose victims who have serious symptoms like passing out or trouble breathing should be given naloxone if available, then called 911. The person should be taken to a poison control center immediately if they are awake and have no symptoms. You can reach your local poison control center by calling 1-800-222-1222. You can contact a poison control center in your province if you live in Canada. An overdose may cause slow/shallow breathing, slow heartbeat, and coma.


Before taking Opana ER 5mg tell your doctor or pharmacist if you are allergic to it; or to other Opana ER 5mg pain medications (such as codeine, morphine, or oxycodone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: brain disorders (such as head injury, tumor, seizures), breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease-COPD), gallbladder disease, kidney disease, liver disease, mental/mood disorders (such as confusion, depression, thoughts of suicide), personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol), stomach/intestinal problems (such as blockage, surgery, constipation, diarrhea due to infection, paralytic ileus), cancer of the esophagus or colon, difficulty swallowing, disease of the pancreas (pancreatitis), difficulty urinating (such as due to enlarged prostate).


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