Hydrocodone 10/325mg is an opioid pain medication.

Zohydro ER and Hysingla ER are extended-release forms of Hydrocodone 10/325mg used for the around-the-clock treatment of severe pain.

Extended-release hydrocodone is not for use on an as-needed basis for pain.

Warnings

Hydrocodone 10/325mg can slow or stop your breathing. Never use this medicine in larger amounts or for longer than prescribed. Do not crush, break, or open an extended-release pill. Swallow it whole to avoid exposure to a potentially fatal dose.

Hydrocodone 10/325mg may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

How should I take hydrocodone?

Hydrocodone 10/325mg may be habit-forming, even at regular doses. Follow the directions on your prescription label and read all medication guides. Never use hydrocodone in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of this medicine.

Do not share opioid medicine with anyone, especially if they have a history of drug abuse or addiction. Keep the medication away from others so it cannot be misused. Misuse can lead to addiction, overdose, or death. Opioid medicine cannot be sold or given away.

Dosing information

Usual Adult Dose for Chronic Pain:

The following dosing recommendations can only be considered suggested approaches to what is actually a series of clinical decisions over time; each patient should be managed individually.

As First Opioid Analgesic and For Patients who are NOT Opioid Tolerant:
Extended-Release Capsules (Zohydro(R) ER): Initial dose: 10 mg orally every 12 hours
Extended-Release Tablets (Hysingla(R) ER): Initial dose: 20 mg orally every 24 hours

What happens if I miss a dose?

Since Hydrocodone 10/325mg is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A hydrocodone overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, and slow or no breathing. You may still need emergency medical care and CPR (cardiopulmonary resuscitation) in the meantime.